Neotia Getwel Healthcare Centre, Siliguri successfully treated a very Rare Variant of Guillain-Barre Syndrome on a 5 years old Girl. -Complex Procedure of Plasma Exchange of a Critically Ill Child performed in the North Bengal.

Neotia Getwel Healthcare Centre has always shown clinical advancement with successful outcome in providing top – of – the – line Paediatric Critical Care to treat rare of rare diseases & disorders affecting the children of this region.

Recently a 5 years old girl was admitted to the Emergency Department of Neotia Getwel with walking difficulty (ataxia), restricted eye balls (opthalmoplegia), difficulty in movement of arms and legs (quadriparesis) and drowsiness. She was diagnosed with a very rare variant of Guillain-Barre Syndrome (Atypical Miller Fisher Syndrome) on further investigation.  The entire treatment plan involved a team of Consultants including: Dr. Jeevan Silwal, Consultant – Paediatric Neurology, Dr. Prince Parakh, Consultant – Paediatrics & Neonatology, Dr. Sumantra Kr. Raut, Consultant – Paediatric Nephrology, Dr. Ajit Kr. Singh, Consultant – Nephrology & Dr. Tanmoy Pal , Consultant – Neurology & inputs were taken from other concerned specialty when required.

Guillain-Barre Syndrome (GBS) is a Medical Emergency. It is a rare disorder in which the body’s immune system attacks ones nerves. Weakness and tingling in your extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing the whole body. Guillain-Barre syndrome is a serious condition that requires immediate hospitalization because it can worsen rapidly.

In spite of round the clock care by team of doctors & the PICU team, the girl wasn’t responding well to the treatment. She was suspected to have rare variant of GBS where Serum GQ1b is present in high titres, which was confirmed from her serum. Due to high serum GQ1b antibody positivity, the condition deteriorated so much that she had been comatose for almost a week, needing mechanical ventilation during that period. She wasn’t responding to IV immunoglobulin (IVIg) and thus, a decision of performing Plasmapheresis (plasma exchange – PEX) was taken by the team of doctors to remove the antibody.

Dr. Sumantra Kr. Raut, Consultant – Paediatric Nephrology & Dr. Ajit Kr. Singh, Consultant – Nephrology of Neotia Getwel performed Plasmapheresis to treat her. This rare procedure which, performed in North Bengal proved to be live saving for the patient.

“Plasmapheresis (PEX) is an invasive procedure in which blood is taken out from the patient, the plasma is separated and rejected along with the culprit antibody and fresh plasma, collected from multiple healthy donors is being transfused to the patient. PEX involves intensive monitoring of a patient during and after the procedure particularly in a comatose child where detection of side effects and complication is challenging. This little girl went through 10 sessions of PEX. Later she was weaned off from ventilator and was discharged in a recovering phase. We hope that she will resume her school, play and other day to day activities very soon and can enjoy her childhood like other children”, said Dr. Sumantra Kr. Raut.

As per, Dr. Jeevan Silwal & Dr. Prince Parakh, “After multiple cycles of Plasmapheresis, the girl is now recovering really well. She is completely alert and interacting with everyone.  Weakness has been reduced to a significant level. With rehabilitation & physiotherapy she should be able recover further.  This wouldn’t have been possible without the help of advanced technology and expert team of doctors and nurses of Neotia Getwel who brought life back to the little girl and smile back on the faces of her parents”.

“Seeing your child getting paralysed in front of your eyes is the worst thing that could happen to any parents. When our daughter was comatose, we almost lost hope of getting her back. But with the help of advanced technology, proper diagnosis, round the clock care and team work, we got our daughter back smiling. We are thankful to her doctors and especially the to the entire PICU team who worked day & night to save our child”, said, Mr. Basak, father of the child.

The Department of Paediatrics at Neotia Getwel consists of a separate PICU (Paediatric Intensive Care Unit) with advanced Paediatric ventilators & state – of – the – art monitoring facilities & highly skilled doctors, nurses and supporting staffs to manage a wide range of critical health problems in children.